IFN-γ Production Depends on IL-12 and IL-18 Combined Action and Mediates Host Resistance to Dengue Virus Infection in a Nitric Oxide-Dependent Manner

Dengue is a mosquito-borne disease caused by one of four serotypes of Dengue virus (DENV-1–4). Severe dengue infection in humans is characterized by thrombocytopenia, increased vascular permeability, hemorrhage and shock. However, there is little information about host response to DENV infection. He...

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Detalhes bibliográficos
Main Authors: Fagundes, Caio T., Costa, Vivian V., Cisalpino, Daniel, Amaral, Flávio A., Souza, Patrícia R. S., Souza, Rafael S., Ryffel, Bernhard, Vieira, Leda Q., Silva, Tarcília A., Atrasheuskaya, Alena, Ignatyev, George, Sousa, Lirlândia P., Souza, Danielle G., Teixeira, Mauro M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243710/
https://ncbi.nlm.nih.gov/pubmed/22206036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001449
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