FGF signalling inhibits neural induction in human embryonic stem cells

Human embryonic stem cells (hESCs) can exit the self-renewal programme, through the action of signalling molecules, at any given time and differentiate along the three germ layer lineages. We have systematically investigated the specific roles of three signalling pathways, TGFβ/SMAD2, BMP/SMAD1, and...

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Main Authors: Greber, Boris, Coulon, Philippe, Zhang, Miao, Moritz, Sören, Frank, Stefan, Müller-Molina, Arnoldo José, Araúzo-Bravo, Marcos J, Han, Dong Wook, Pape, Hans-Christian, Schöler, Hans R
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243624/
https://ncbi.nlm.nih.gov/pubmed/22085933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.407
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