FGF signalling inhibits neural induction in human embryonic stem cells

Human embryonic stem cells (hESCs) can exit the self-renewal programme, through the action of signalling molecules, at any given time and differentiate along the three germ layer lineages. We have systematically investigated the specific roles of three signalling pathways, TGFβ/SMAD2, BMP/SMAD1, and...

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Main Authors: Greber, Boris, Coulon, Philippe, Zhang, Miao, Moritz, Sören, Frank, Stefan, Müller-Molina, Arnoldo José, Araúzo-Bravo, Marcos J, Han, Dong Wook, Pape, Hans-Christian, Schöler, Hans R
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243624/
https://ncbi.nlm.nih.gov/pubmed/22085933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.407
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