SUMOylation and SUMO-interacting Motif (SIM) of Metastasis Tumor Antigen 1 (MTA1) Synergistically Regulate Its Transcriptional Repressor Function

Metastasis tumor antigen 1 (MTA1), a component of the Mi-2·nucleosome remodeling and deacetylase complex, plays a crucial role in gene transcription, but the mechanism involved remains largely unknown. Here, we report that MTA1 is a substrate for small ubiquitin-related modifier 2/3 (SUMO2/3) in viv...

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Bibliografiske detaljer
Main Authors: Cong, Lin, Pakala, Suresh B., Ohshiro, Kazufumi, Li, Da-Qiang, Kumar, Rakesh
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243521/
https://ncbi.nlm.nih.gov/pubmed/21965678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.267237
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