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Comprehensive Genome-wide Protein-DNA Interactions Detected at Single Nucleotide Resolution
Chromatin immunoprecipitation (ChIP-chip and ChIP-seq) assays identify where proteins bind throughout a genome. However, DNA contamination and DNA fragmentation heterogeneity produce false positives (erroneous calls) and imprecision in mapping. Consequently, stringent data filtering produces false n...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3243364/ https://ncbi.nlm.nih.gov/pubmed/22153082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.11.013 |
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