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Genome-wide structure and organization of eukaryotic pre-initiation complexes

The structural and positional organization of transcription pre-initiation complexes (PICs) across eukaryotic genomes is unknown. We employed ChIP-exo to precisely examine ~6,000 PICs in Saccharomyces. PICs, including RNA polymerase II and general factors TFIIA, -B, -D/TBP, -E, -F, -H, and -K were p...

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Bibliographische Detailangaben
Hauptverfasser: Rhee, Ho Sung, Pugh, B. Franklin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306527/
https://ncbi.nlm.nih.gov/pubmed/22258509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10799
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