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Genomic organization of human transcription initiation complexes
The human genome is pervasively transcribed, yet only a small fraction is coding. Here we address whether this noncoding transcription arises at promoters, and detail the interactions of initiation factors TBP, TFIIB, and RNA polymerase (Pol) II. Using ChIP-exo, we identify ~160,000 transcription in...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018585/ https://ncbi.nlm.nih.gov/pubmed/24048476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12535 |
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