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Genomic organization of human transcription initiation complexes

The human genome is pervasively transcribed, yet only a small fraction is coding. Here we address whether this noncoding transcription arises at promoters, and detail the interactions of initiation factors TBP, TFIIB, and RNA polymerase (Pol) II. Using ChIP-exo, we identify ~160,000 transcription in...

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Bibliografische gegevens
Hoofdauteurs: Venters, Bryan J., Pugh, B. Franklin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018585/
https://ncbi.nlm.nih.gov/pubmed/24048476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12535
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