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ChIP-exo: A Method to Identify Genomic Location of DNA-binding proteins at Near Single Nucleotide Accuracy

This unit describes ChIP-exo methodology, which involves chromatin immunoprecipitation (ChIP) combined with lambda exonuclease digestion followed by high-throughput sequencing. ChIP-exo allows us to identify a nearly complete set of binding locations of DNA-bound proteins at near single nucleotide r...

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Detalles Bibliográficos
Main Authors: Rhee, Ho Sung, Pugh, B. Franklin
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813302/
https://ncbi.nlm.nih.gov/pubmed/23026909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142727.mb2124s100
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