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Pharmacological blockade of corticotropin-releasing hormone receptor 1 (CRH1R) reduces voluntary consumption of high alcohol concentrations in non-dependent Wistar rats

BACKGROUND: A dysregulation of the corticotropin-releasing hormone (CRH) system has been implicated in the development of excessive alcohol consumption and dependence. The aim of the present study was to evaluate whether the CRH system is also recruited when non-dependent Wistar rats escalate to hig...

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Bibliographic Details
Main Authors: Cippitelli, Andrea, Damadzic, Ruslan, Singley, Erick, Thorsell, Annika, Ciccocioppo, Roberto, Eskay, Robert L., Heilig, Markus
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242882/
https://ncbi.nlm.nih.gov/pubmed/22036774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2011.10.016
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