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Binge-Like Ethanol Consumption Increases Corticosterone Levels and Neurodegneration whereas occupancy of Type II Glucocorticoid Receptors with Mifepristone is Neuroprotective

Excessive ethanol (EtOH) use leads to impaired memory and cognition. Using a rat model of binge-like intoxication, we tested whether elevated corticosterone (Cort) levels contribute to the neurotoxic consequences of EtOH exposure. Rats were adrenalectomized (Adx) and implanted with cholesterol pelle...

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Main Authors:	Cippitelli, Andrea, Damadzic, Ruslan, Hamelink, Carol, Brunnquell, Michael, Thorsell, Annika, Heilig, Markus, Eskay, Robert L
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	2012
נושאים:	Article
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3561503/ https://ncbi.nlm.nih.gov/pubmed/22500955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2012.00451.x
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Binge-Like Ethanol Consumption Increases Corticosterone Levels and Neurodegneration whereas occupancy of Type II Glucocorticoid Receptors with Mifepristone is Neuroprotective

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