PiggyBac-mediated Cancer Immunotherapy Using EBV-specific Cytotoxic T-cells Expressing HER2-specific Chimeric Antigen Receptor

Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes (CTLs) can be modified to function as heterologous tumor directed effector cells that survive longer in vivo than tumor directed T cells without virus specificity, due to chronic stimulation by viral antigens expressed during persistent infec...

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Detalhes bibliográficos
Main Authors: Nakazawa, Yozo, Huye, Leslie E, Salsman, Vita S, Leen, Ann M, Ahmed, Nabil, Rollins, Lisa, Dotti, Gianpietro, Gottschalk, Stephen M, Wilson, Matthew H, Rooney, Cliona M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242651/
https://ncbi.nlm.nih.gov/pubmed/21772253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.131
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