Targeting PIM kinase enhances the activity of sunitinib in renal cell carcinoma

BACKGROUND: Upregulation of PIM kinase expression has been reported in many malignancies, suggesting that inhibition of PIM kinase activity may be an attractive therapeutic strategy. We hypothesised that inhibition of PIM kinase activity with SGI-1776, a novel small molecule inhibitor of PIM kinase...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Mahalingam, D, Espitia, C M, Medina, E C, Esquivel, J A, Kelly, K R, Bearss, D, Choy, G, Taverna, P, Carew, J S, Giles, F J, Nawrocki, S T
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
Matèries:
Translational Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242528/
https://ncbi.nlm.nih.gov/pubmed/22015557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.426
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars