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Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1
Beclin 1, a subunit of the class III phosphatidylinositol 3-kinase complex, is a tumour suppressor with a central role in endocytic trafficking, cytokinesis and the cross-regulation between autophagy and apoptosis. Interestingly, not only reduced expression but also overexpression of Beclin 1 is cor...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Portland Press Ltd.
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3242507/ https://ncbi.nlm.nih.gov/pubmed/21936852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111424 |
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