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The Mu-Opioid Receptor and the NMDA Receptor Associate in PAG Neurons: Implications in Pain Control
The capacity of opioids to alleviate inflammatory pain is negatively regulated by the glutamate-binding N-methyl--aspartate receptor (NMDAR). Increased activity of this receptor complicates the clinical use of opioids to treat persistent neuropathic pain. Immunohistochemical and ultrastructural stud...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3242298/ https://ncbi.nlm.nih.gov/pubmed/21814188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.155 |
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