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The Mu-Opioid Receptor and the NMDA Receptor Associate in PAG Neurons: Implications in Pain Control

The capacity of opioids to alleviate inflammatory pain is negatively regulated by the glutamate-binding N-methyl--aspartate receptor (NMDAR). Increased activity of this receptor complicates the clinical use of opioids to treat persistent neuropathic pain. Immunohistochemical and ultrastructural stud...

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Autors principals: Rodríguez-Muñoz, María, Sánchez-Blázquez, Pilar, Vicente-Sánchez, Ana, Berrocoso, Esther, Garzón, Javier
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242298/
https://ncbi.nlm.nih.gov/pubmed/21814188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.155
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