OCRL controls trafficking through early endosomes via PtdIns4,5P(2)-dependent regulation of endosomal actin

Mutations in the phosphatidylinositol 4,5-bisphosphate (PtdIns4,5P(2)) 5-phosphatase OCRL cause Lowe syndrome, which is characterised by congenital cataracts, central hypotonia, and renal proximal tubular dysfunction. Previous studies have shown that OCRL interacts with components of the endosomal m...

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Detaylı Bibliyografya
Asıl Yazarlar: Vicinanza, Mariella, Di Campli, Antonella, Polishchuk, Elena, Santoro, Michele, Di Tullio, Giuseppe, Godi, Anna, Levtchenko, Elena, De Leo, Maria Giovanna, Polishchuk, Roman, Sandoval, Lisette, Marzolo, Maria-Paz, De Matteis, Maria Antonietta
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242071/
https://ncbi.nlm.nih.gov/pubmed/21971085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.354
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