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Kisspeptin-10, a KISS1-Derived Decapeptide, Inhibits Tumor Angiogenesis by Suppressing Sp1-mediated VEGF Expression and FAK/Rho GTPase Activation

Kisspeptin-10 (Kp-10), a decapeptide derived from the primary translation product of KISS1 gene, has been previously reported to be a key hormone for puberty and an inhibitor for tumor metastasis via the activation of G protein-coupled receptor 54 (Gpr54). However, whether Kp-10 inhibits angiogenesi...

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Hlavní autoři: Cho, Sung-Gook, Yi, Zhengfang, Pang, Xiufeng, Yi, Tingfang, Wang, Ying, Luo, Jian, Wu, Zirong, Li, Dali, Liu, Mingyao
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242001/
https://ncbi.nlm.nih.gov/pubmed/19671799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0476
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