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KiSS1 suppresses TNFα-induced breast cancer cell invasion via an inhibition of RhoA-mediated NF-κB activation
Tumor necrosis factor-alpha (TNFα) induces cancer development and metastasis, which is prominently achieved by nuclear factor-kappa B (NF-κB) activation. TNFα-induced NF-κB activation enhances cellular mechanisms including proliferation, migration, and invasion. KiSS1, a key regulator of puberty, wa...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745330/ https://ncbi.nlm.nih.gov/pubmed/19533666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22216 |
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