A Novel Peptide from Human Apolipoprotein(a) Inhibits Angiogenesis and Tumor Growth by Targeting c-Src Phosphorylation in VEGF-induced Human Umbilical Endothelial Cells

Many angiogenesis inhibitors are derived from large plasma proteins. Previous studies showed that the Kringle5-like domain (termed KV) in human Apolipoprotein (a) is a potential antiangiogenic factor. However, its active region and the underling molecular mechanism remain elusive. Here, we identifie...

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Autori principali: Yi, Zheng-Fang, Cho, Sung-Gook, Zhao, Hui, Wu, Yuan-yuan, Luo, Jian, Li, Dali, Yi, Tingfang, Xu, Xun, Wu, Zirong, Liu, Mingyao
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724604/
https://ncbi.nlm.nih.gov/pubmed/19035465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24027
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