Cell transformation assays for prediction of carcinogenic potential: state of the science and future research needs

Cell transformation assays (CTAs) have long been proposed as in vitro methods for the identification of potential chemical carcinogens. Despite showing good correlation with rodent bioassay data, concerns over the subjective nature of using morphological criteria for identifying transformed cells an...

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Autori principali: Creton, Stuart, Aardema, Marilyn J., Carmichael, Paul L., Harvey, James S., Martin, Francis L., Newbold, Robert F., O’Donovan, Michael R., Pant, Kamala, Poth, Albrecht, Sakai, Ayako, Sasaki, Kiyoshi, Scott, Andrew D., Schechtman, Leonard M., Shen, Rhine R., Tanaka, Noriho, Yasaei, Hemad
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
Soggetti:
Meeting Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241940/
https://ncbi.nlm.nih.gov/pubmed/21852270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/ger053
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