Regulation of SNAIL1 and E-cadherin function by DNMT1 in a DNA methylation-independent context

Mammalian DNA methyltransferase 1 (DNMT1) is essential for maintaining DNA methylation patterns after cell division. Disruption of DNMT1 catalytic activity results in whole genome cytosine demethylation of CpG dinucleotides, promoting severe dysfunctions in somatic cells and during embryonic develop...

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Detalles Bibliográficos
Autores principales: Espada, Jesús, Peinado, Hector, Lopez-Serra, Lidia, Setién, Fernando, Lopez-Serra, Paula, Portela, Anna, Renart, Jaime, Carrasco, Elisa, Calvo, María, Juarranz, Angeles, Cano, Amparo, Esteller, Manel
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2011
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241660/
https://ncbi.nlm.nih.gov/pubmed/21846773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr658
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