Regulation of SNAIL1 and E-cadherin function by DNMT1 in a DNA methylation-independent context

Mammalian DNA methyltransferase 1 (DNMT1) is essential for maintaining DNA methylation patterns after cell division. Disruption of DNMT1 catalytic activity results in whole genome cytosine demethylation of CpG dinucleotides, promoting severe dysfunctions in somatic cells and during embryonic develop...

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Dettagli Bibliografici
Autori principali: Espada, Jesús, Peinado, Hector, Lopez-Serra, Lidia, Setién, Fernando, Lopez-Serra, Paula, Portela, Anna, Renart, Jaime, Carrasco, Elisa, Calvo, María, Juarranz, Angeles, Cano, Amparo, Esteller, Manel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Gene Regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241660/
https://ncbi.nlm.nih.gov/pubmed/21846773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr658
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