Comparative characterization of the PvuRts1I family of restriction enzymes and their application in mapping genomic 5-hydroxymethylcytosine

PvuRts1I is a modification-dependent restriction endonuclease that recognizes 5-hydroxymethylcytosine (5hmC) as well as 5-glucosylhydroxymethylcytosine (5ghmC) in double-stranded DNA. Using PvuRts1I as the founding member, we define a family of homologous proteins with similar DNA modification-depen...

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Bibliografiske detaljer
Main Authors: Wang, Hua, Guan, Shengxi, Quimby, Aine, Cohen-Karni, Devora, Pradhan, Sriharsa, Wilson, Geoffrey, Roberts, Richard J., Zhu, Zhenyu, Zheng, Yu
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Nucleic Acid Enzymes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241641/
https://ncbi.nlm.nih.gov/pubmed/21813453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr607
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