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Characterization of the 5-hydroxymethylcytosine-specific DNA restriction endonucleases

In T4 bacteriophage, 5-hydroxymethylcytosine (5hmC) is incorporated into DNA during replication. In response, bacteria may have developed modification-dependent type IV restriction enzymes to defend the cell from T4-like infection. PvuRts1I was the first identified restriction enzyme to exhibit spec...

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Bibliografiske detaljer
Main Authors: Borgaro, Janine G., Zhu, Zhenyu
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627594/
https://ncbi.nlm.nih.gov/pubmed/23482393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt102
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