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A unique family of Mrr-like modification-dependent restriction endonucleases

Mrr superfamily of homologous genes in microbial genomes restricts modified DNA in vivo. However, their biochemical properties in vitro have remained obscure. Here, we report the experimental characterization of MspJI, a remote homolog of Escherichia coli’s Mrr and show it is a DNA modification-depe...

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Detalhes bibliográficos
Main Authors: Zheng, Yu, Cohen-Karni, Devora, Xu, Derrick, Chin, Hang Gyeong, Wilson, Geoffrey, Pradhan, Sriharsa, Roberts, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938202/
https://ncbi.nlm.nih.gov/pubmed/20444879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq327
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