Overexpression of cIAP2 contributes to 5-FU resistance and a poor prognosis in oral squamous cell carcinoma

BACKGROUND: Resistance to 5-fluorouracil (5-FU) is a major obstacle in treating oral squamous cell carcinoma (OSCC). However, little is known about apoptosis resistance, which contributes to 5-FU resistance in OSCC. METHODS: We focussed on the cellular inhibitor of apoptosis protein 2 (cIAP2) on the...

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Bibliografische gegevens
Hoofdauteurs: Nagata, M, Nakayama, H, Tanaka, T, Yoshida, R, Yoshitake, Y, Fukuma, D, Kawahara, K, Nakagawa, Y, Ota, K, Hiraki, A, Shinohara, M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2011
Onderwerpen:
Translational Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241556/
https://ncbi.nlm.nih.gov/pubmed/21952624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.387
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