IL-6 controls resistance to radiation by suppressing oxidative stress via the Nrf2-antioxidant pathway in oral squamous cell carcinoma

BACKGROUND: In promoting tumour malignancy IL-6 signalling is considered to have an important role. However, the biological roles of IL-6 on radiosensitivity in oral squamous cell carcinoma (OSCC) remain largely unclear. The objective of this study is to determine the effects and molecular mechanism...

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Foilsithe in:Br J Cancer
Main Authors: Matsuoka, Yuichiro, Nakayama, Hideki, Yoshida, Ryoji, Hirosue, Akiyuki, Nagata, Masashi, Tanaka, Takuya, Kawahara, Kenta, Sakata, Junki, Arita, Hidetaka, Nakashima, Hikaru, Shinriki, Satoru, Fukuma, Daiki, Ogi, Hidenao, Hiraki, Akimitsu, Shinohara, Masanori, Toya, Ryo, Murakami, Ryuji
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Translational Therapeutics
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104896/
https://ncbi.nlm.nih.gov/pubmed/27736845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.327
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