Predictive value of the combination of SMAD4 expression and lymphocyte infiltration in malignant transformation of oral leukoplakia

Oral leukoplakia (OL) is a common, potentially malignant disorder of the oral cavity. SMAD4 was initially identified as a tumor suppressor and central mediator of transforming growth factor (TGF)‐β signaling. In this study, we aimed to determine the expression patterns of SMAD4 in OL, its relationsh...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Sakata, Junki, Yoshida, Ryoji, Matsuoka, Yuichiro, Nagata, Masashi, Hirosue, Akiyuki, Kawahara, Kenta, Nakamura, Takuya, Nakamoto, Masafumi, Hirayama, Masatoshi, Takahashi, Nozomu, Nakashima, Hikaru, Arita, Hidetaka, Ogi, Hidenao, Hiraki, Akimitsu, Shinohara, Masanori, Nakayama, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Clinical Cancer Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387127/
https://ncbi.nlm.nih.gov/pubmed/28256094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1005
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