Synthesis and Properties of Molecular Probes for the Rescue Site on Mutant Cystic Fibrosis Transmembrane Conductance Regulator

[Image: see text] Cystic fibrosis is a genetic disease caused by mutations in the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. In vitro experiments have demonstrated that 4-methyl-2-(5-phenyl-1H-pyrazol-3-yl)phenol (VRT-532, 1) is able to partially restore the fun...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Alkhouri, Bashar, Denning, Robert A., Kim Chiaw, Patrick, Eckford, Paul D. W., Yu, Wilson, Li, Canhui, Bogojeski, Jovanka J., Bear, Christine E., Viirre, Russell D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2011
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241338/
https://ncbi.nlm.nih.gov/pubmed/22074181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201335c
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi