Facilitating adverse drug event detection in pharmacovigilance databases using molecular structure similarity: application to rhabdomyolysis

BACKGROUND: Adverse drug events (ADE) cause considerable harm to patients, and consequently their detection is critical for patient safety. The US Food and Drug Administration maintains an adverse event reporting system (AERS) to facilitate the detection of ADE in drugs. Various data mining approach...

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Autores principales: Vilar, Santiago, Harpaz, Rave, Chase, Herbert S, Costanzi, Stefano, Rabadan, Raul, Friedman, Carol
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Group 2011
Materias:
Research and Applications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241177/
https://ncbi.nlm.nih.gov/pubmed/21946238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/amiajnl-2011-000417
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