Facilitating adverse drug event detection in pharmacovigilance databases using molecular structure similarity: application to rhabdomyolysis

BACKGROUND: Adverse drug events (ADE) cause considerable harm to patients, and consequently their detection is critical for patient safety. The US Food and Drug Administration maintains an adverse event reporting system (AERS) to facilitate the detection of ADE in drugs. Various data mining approach...

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Главные авторы: Vilar, Santiago, Harpaz, Rave, Chase, Herbert S, Costanzi, Stefano, Rabadan, Raul, Friedman, Carol
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Group 2011
Предметы:
Research and Applications
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241177/
https://ncbi.nlm.nih.gov/pubmed/21946238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/amiajnl-2011-000417
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