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Polycomb Repressed Genes have Permissive Enhancers that Initiate Reprogramming
Key regulatory genes, suppressed by Polycomb and H3K27me3, become active during normal differentiation and induced reprogramming. Using the well-characterized enhancer/promoter pair of MYOD1 as a model, we have identified a critical role for enhancers in reprogramming. We observed an unexpected nucl...
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| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3240866/ https://ncbi.nlm.nih.gov/pubmed/22153073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.10.040 |
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