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Polycomb Repressed Genes have Permissive Enhancers that Initiate Reprogramming
Key regulatory genes, suppressed by Polycomb and H3K27me3, become active during normal differentiation and induced reprogramming. Using the well-characterized enhancer/promoter pair of MYOD1 as a model, we have identified a critical role for enhancers in reprogramming. We observed an unexpected nucl...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3240866/ https://ncbi.nlm.nih.gov/pubmed/22153073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.10.040 |
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