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Downregulation of the serum response factor/miR-1 axis in the quadriceps of patients with COPD
RATIONALE: Muscle atrophy confers a poor prognosis in patients with chronic obstructive pulmonary disease (COPD), yet the molecular pathways responsible are poorly characterised. Muscle-specific microRNAs and serum response factor (SRF) are important regulators of muscle phenotype that contribute to...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BMJ Group
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3240776/ https://ncbi.nlm.nih.gov/pubmed/21998125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2011-200309 |
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