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Arl8 and SKIP Act Together to Link Lysosomes to Kinesin-1
Lysosomes move bidirectionally on microtubules, and this motility can be stimulated by overexpression of the small GTPase Arl8. By using affinity chromatography, we find that Arl8-GTP binds to the soluble protein SKIP (SifA and kinesin-interacting protein, aka PLEKHM2). SKIP was originally identifie...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cell Press
2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3240744/ https://ncbi.nlm.nih.gov/pubmed/22172677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.10.007 |
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