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Arl8 and SKIP Act Together to Link Lysosomes to Kinesin-1

Lysosomes move bidirectionally on microtubules, and this motility can be stimulated by overexpression of the small GTPase Arl8. By using affinity chromatography, we find that Arl8-GTP binds to the soluble protein SKIP (SifA and kinesin-interacting protein, aka PLEKHM2). SKIP was originally identifie...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rosa-Ferreira, Cláudia, Munro, Sean
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240744/
https://ncbi.nlm.nih.gov/pubmed/22172677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.10.007
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