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Hydroxyl Radical (OH(•)) Reaction with Guanine in an Aqueous Environment: A DFT Study

The reaction of hydroxyl radical (OH(•)) with DNA accounts for about half of radiation-induced DNA damage in living systems. Previous literature reports point out that the reaction of OH(•) with DNA proceeds mainly through the addition of OH(•) to the C=C bond of the DNA bases. However, recently it...

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Hlavní autoři: Kumar, Anil, Pottiboyina, Venkata, Sevilla, Michael D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240735/
https://ncbi.nlm.nih.gov/pubmed/22050033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp208841q
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