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Francisella infection triggers activation of the AIM2 inflammasome in murine dendritic cells
The intracellular bacterium Francisella tularensis is the causative agent of tularemia, a potentially fatal disease. In macrophages, Francisella escapes the initial phagosome and replicates in the cytosol, where it is detected by the cytosolic DNA sensor AIM2 leading to activation of the AIM2 inflam...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3240688/ https://ncbi.nlm.nih.gov/pubmed/21902795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2011.01700.x |
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