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Preparation procedures of proteins and RNA influence the total reconstitution of 50S subunits from E. coli ribosomes.

A two-step procedure has been described for the total reconstitution of 50S ribosomal subunit from E. coli. RNA and proteins are mixed with stoichiometry of 1:1.2 and incubated at 44 degrees C in 4.0 mM Mg2+ followed by a second incubation at 50 degrees C in 20 mM Mg2+ (Dohme and Nierhaus, J. Mol. B...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Nowotny, V, Rheinberger, H J, Nierhaus, K, Tesche, B, Amils, R
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 1980
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323967/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6160479/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/8.5.989
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