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Pancreatic B cells possess defense mechanisms against cell-specific toxicity.

Insulin-dependent diabetes develops when more than 90% of the insulin containing B cells are destroyed. The present study investigates whether the target B cells can counteract the damaging effects of cytotoxic substances. Purified islet cells were first exposed for 3-10 min to t-butylhydroperoxide,...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Pipeleers, D, Van de Winkel, M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323932/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2941762/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.5267
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