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Pancreatic B cells possess defense mechanisms against cell-specific toxicity.

Insulin-dependent diabetes develops when more than 90% of the insulin containing B cells are destroyed. The present study investigates whether the target B cells can counteract the damaging effects of cytotoxic substances. Purified islet cells were first exposed for 3-10 min to t-butylhydroperoxide,...

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Detalhes bibliográficos
Main Authors: Pipeleers, D, Van de Winkel, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC323932/
https://ncbi.nlm.nih.gov/pubmed/2941762
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