Pancreatic B cells possess defense mechanisms against cell-specific toxicity.
Insulin-dependent diabetes develops when more than 90% of the insulin containing B cells are destroyed. The present study investigates whether the target B cells can counteract the damaging effects of cytotoxic substances. Purified islet cells were first exposed for 3-10 min to t-butylhydroperoxide,...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323932/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2941762/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.5267 |
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