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Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent.

Salmonella typhimurium is a facultative intracellular pathogen capable of surviving within phagocytic cells of the reticuloendothelial system. To identify the genes important for intracellular survival, 9516 independent Tn10 insertional mutations were isolated in a virulent strain of S. typhimurium....

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Fields, P I, Swanson, R V, Haidaris, C G, Heffron, F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1986
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323916/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3523484/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.5189
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