Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent.

Salmonella typhimurium is a facultative intracellular pathogen capable of surviving within phagocytic cells of the reticuloendothelial system. To identify the genes important for intracellular survival, 9516 independent Tn10 insertional mutations were isolated in a virulent strain of S. typhimurium....

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Fields, P I, Swanson, R V, Haidaris, C G, Heffron, F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323916/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3523484/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.5189
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