Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent.
Salmonella typhimurium is a facultative intracellular pathogen capable of surviving within phagocytic cells of the reticuloendothelial system. To identify the genes important for intracellular survival, 9516 independent Tn10 insertional mutations were isolated in a virulent strain of S. typhimurium....
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323916/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3523484/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.5189 |
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