Relative Tissue Factor Deficiency Attenuates Ventilator-Induced Coagulopathy but Does Not Protect against Ventilator-Induced Lung Injury in Mice

Preventing tissue-factor-(TF-) mediated systemic coagulopathy improves outcome in models of sepsis. Preventing TF-mediated pulmonary coagulopathy could attenuate ventilator-induced lung injury (VILI). We investigated the effect of relative TF deficiency on pulmonary coagulopathy and inflammation in...

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Detalhes bibliográficos
Main Authors: Wolthuis, Esther K., Vlaar, Alexander P. J., Choi, Goda, Roelofs, Joris J. T. H., Levi, Marcel, Juffermans, Nicole P., Schultz, Marcus J.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3238356/
https://ncbi.nlm.nih.gov/pubmed/22195278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/130410
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