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Vesicular distribution of Secretory Pathway Ca(2+)-ATPase isoform 1 and a role in manganese detoxification in liver-derived polarized cells

Manganese is a trace element that is an essential co-factor in many enzymes critical to diverse biological pathways. However, excess Mn(2+) leads to neurotoxicity, with psychiatric and motor dysfunction resembling parkinsonism. The liver is the main organ for Mn(2+) detoxification by excretion into...

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Detalhes bibliográficos
Main Authors: Leitch, Sharon, Feng, Mingye, Muend, Sabina, Braiterman, Lelita T., Hubbard, Ann L., Rao, Rajini
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3238027/
https://ncbi.nlm.nih.gov/pubmed/20981470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10534-010-9384-3
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