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Vesicular distribution of Secretory Pathway Ca(2+)-ATPase isoform 1 and a role in manganese detoxification in liver-derived polarized cells
Manganese is a trace element that is an essential co-factor in many enzymes critical to diverse biological pathways. However, excess Mn(2+) leads to neurotoxicity, with psychiatric and motor dysfunction resembling parkinsonism. The liver is the main organ for Mn(2+) detoxification by excretion into...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3238027/ https://ncbi.nlm.nih.gov/pubmed/20981470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10534-010-9384-3 |
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