Eosinophils as a novel cell source of prostaglandin D2: autocrine role in allergic inflammation

Prostaglandin (PG)D(2) is a key mediator of allergic inflammatory diseases that is mainly synthesized by mast cells, which constitutively express high levels of the terminal enzyme involved in PGD(2) synthesis, the hematopoietic PGD synthase (H-PGDS). Here, we investigated whether eosinophils are al...

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Autori principali: Luna-Gomes, Tatiana, Magalhães, Kelly G, Mesquita-Santos, Fabio P., Bakker-Abreu, Ilka, Samico, Rafaela F., Molinaro, Raphael, Calheiros, Andrea S., Diaz, Bruno L., Bozza, Patrícia T., Weller, Peter F., Bandeira-Melo, Christianne
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237921/
https://ncbi.nlm.nih.gov/pubmed/22102725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101806
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