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TGFβ and BMP-2 regulate epicardial cell invasion via TGFβR3 activation of the Par6/Smurf1/RhoA pathway

Coronary vessel development requires transfer of mesothelial cells to the heart surface to form the epicardium where some cells subsequently undergo epithelial-mesenchymal transformation (EMT) and invade the subepicardial matrix. Tgfbr3(-/-) mice die due to failed coronary vessel formation associate...

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Bibliografische gegevens
Hoofdauteurs: Sánchez, Nora S., Barnett, Joey V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237859/
https://ncbi.nlm.nih.gov/pubmed/22033038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.10.006
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