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Granzyme B Regulates Antiviral CD8(+) T cell Responses(1)
Cytotoxic T lymphocytes and natural killer cells utilize the perforin/granzyme cytotoxic pathway to kill virally-infected cells and tumors. Human regulatory T cells also express functional granzymes and perforin and can induce autologous target cell death in vitro. Perforin-deficient mice die from e...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3237805/ https://ncbi.nlm.nih.gov/pubmed/22084442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100891 |
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